Yoga and Infertility

 Although the new pandemic of coronavirus has temporarily covered the whole world, as it subsides, the old problem of infertility is rearing its head once again. Current statistics indicate that 1 out of every 6 couples in India is infertile and that the rate of infertility is increasing over time. A lot of infertility treatments are available – but before going in for treatment, any infertile couple has to consider additional measures to boost fertility.

If one briefly surveys the causes of infertility, one might find reasons like obesity, stress, tension and lack of time and physical exercise. It is a fact that disease – like infertility – may be caused not only by physical factors but also by mental and spiritual distress. Health is defined as a state of complete physical, mental and spiritual well-being and lack of any one of these factors may manifest in a physical form. Treatment of these causes may break the chain that leads to infertility and potentially avoid infertility treatments.

Yoga is an ancient Indian system aimed at keeping one’s body, mind and soul healthy and fit. In today’s stressful world the practice of yoga is ideally suited towards restoring the balance of one’s life and making oneself physically and mentally fit. The practice of yoga comprises physical and breathing exercises – also called as pranayama – and meditation. It is a complete amalgamation of these three elements which transform one’s body, mind and soul and allows one to reach a state of complete bliss.

As a word of caution, one should be careful not to get seduced by unscrupulous or improperly trained persons. As is the case with all disciplines, yoga has to be learnt from a competent teacher or Guru. Also important is to remain focused and patient and keep working regularly and honestly.

The practice of yoga and regular exercise helps in reducing some cases of infertility and avoiding costly infertility treatments. So, start now or you want any tips contact- Jindal IVF

Role of Genetics in Male and Female Infertility

Reproduction in any species,is a highly complicated process. It involves co-ordination at several different steps. All of these processes are tightly regulated by a number of genes and thereby require the proper functioning of these genes.

Gene is a unit of DNA, present in every human, which is important for the transfer of hereditary traits to children. Abnormality in any of these may lead to various problems including infertility.

Infertility is the inability to achieve pregnancy (technically within 1 year of marriage), assuming regular intercourse between the couple. Childlessness is a serious issue, carrying major negative psychological impact on couples, and social stigma, especially in a developing countries like ours.

The basis of infertility is also varied and involves a complex interplay of several gene products. It has been estimated that nearly 30% of infertility cases are due to genetic defects.

Genetic disease means any abnormality in one’s genetic make up – involving genes or chromosomes (a group of genes). There can be many types of chromosomal abnormalities like a missing piece of a chromosome (deletion), change in the gene’s DNA sequence (mutation), change in the total number of chromosomes (aneuploidy) etc.

Even if pregnancy does happen, chromosomally abnormal embryos often lead to miscarriages or to the birth of babies with physical or mental abnormalities.

Presently only a few genetic abnormalities are considered to be associated with infertility, but in this era of complete human genome mapping, personalized medicine is rapidly coming to the forefront.

While discussing all the genetic diseases here would be futile, let us focus on the most important ones.

MALE INFERTILITY

Chromosomal abnormalities are detected in up to 20% of infertile men with severe semen defects like azoospermia, and severe oligozoospermia. Some of the common genetic defects that causes male infertility are:-

Klinefelter Syndrome  – 47,XXY(normal male is 46 XY) i.e. presence of an extra X chromosome in a male. It is the most common chromosomal aberration detected in up to 14% of infertile patients with azoospermia.

Klinefelter patients show multiple other features like a tall male with less body hair, weak muscles, learning and behavioral problems. There is high risk of chromosomal abnormalities in their children, even if these men manage to father one.

47,XYY Syndrome -This syndrome is rare, but is more common among infertile males. These men with the 47,XYY karyotype (i.e.an extra y chromosome)are otherwise healthy but semen analyses is usually abnormal.

Structural Chromosomal Abnormalities – This  include deletions, duplications, translocations and inversions. Overall, these occur in nearly 5% in infertile men. Apart from infertility, wives of these males are prone to abortions too.

Y Chromosome Microdeletions -This is an important microdeletion associated with male infertility. It involves abnormalities in the Y chromosome, and as this chromosome is present only in males, this problem affects the males exclusively. AZFc type of deletions are found more commonly in India. This type of genetic abnormality can be passed from father to son, making it particularly important to be ruled out prior to planning conception.

Testicular Disorder of Sex Development (DSD)  – The DSD (46,XX male syndrome) is a rare disease. 46,XX males with testicular DSD have normal male genitalia, but develop abnormal sperm formation over time and even testicular shrinking.

CBAVD – The most common single-gene disorder is congenital bilateral aplasia of the vas deferens (CBAVD) i.e. the absence of the tube carrying sperms out of the testes. This leads to complete absence of sperms in the semen(azoospermia). Complete mutation this gene results in classical cystic fibrosis syndrome, including multiple other clinical symptoms and male infertility.

FEMALE INFERTILITY

Multiple genes are involved in formation of hormones determining sequence of formation of the reproductive organs during the course development of a female body. Any defect in the interplay of these hormones leads to the abnormality in the development of the female organs like the uterus, fallopian tubes or the ovaries-a finding not so uncommon in the setting of female infertility. Premature ovarian failure(early menopause)is also quite routinely seen in this population.

Primary Ovarian Failure (POF)
Ovaries release the female hormones, responsible for the maintenance of female characters. Primary ovarian failure is the failure of the ovaries to function. So the woman presents with early menopause(stopping of monthly periods)and infertility. Several genes maybe associated with this disease.

47,XXX  – Also known as trisomy X , is one of most common causes of premature ovarian failure.

Down syndrome – Down syndrome is usually associated with advanced age of the mother and is one the commonest genetic disorders. It is caused by the presence of an extra chromosome (three instead of two) in position 21. It is also referred to as trisomy 21.

Turner syndrome – Also known as monosomy X or 45,XO.These woman have abnormalities of the skeletal system(bones),heart,short height and non functional ovaries.The milder forms of his syndrome(mosaics)often present with infertility.

Fragile X syndrome  – This a disorder characterized mainly by mental retardation and facial abnormalities. Infertility is common and at times runs in families so females having sisters or other family members suffering from infertility should get themselves tested at an infertility clinic at the earliest.

Galactosemia – This is a metabolic disorder related to improper utilisation of a sugar in the body. It has a strong genetic basis. Genetic counselling and medical intervention is very useful in families with this disease..

Polycystic Ovarian Syndrome(PCOS) – PCOS is a highly complex hormonal condition that affects 8-10% of women of the reproductive age group. PCOS is marked by excess of male hormones in the female and abnormality of sugar control, leading to multiple problems like irregular periods, weight gain, excessive hair growth, skin changes etc.

A large number of these women suffer from infertility as the egg release from the ovary(ovulation) is often defective. Early and persistent treatment with an infertility specialist leads to successful child bearing in a large majority of these patients. Multiple genes governing the sugar control and sex hormone regulation are involved.

Androgen Insensitivity Syndrome (AIS) – It is a very peculiar condition where when a person who is genetically male (who has one X and one Y chromosome) is resistant to male hormones and as a result, looks completely like a female externally.This “she” can never conceive. AIS is caused by genetic defects on the y chromosome.

Genetics of Infertility Common to Both Sexes:

Cystic fibrosis – Patients with CF suffer from systemic disorders in multiple organ disorders, including infertility. In males, there may often be the absence of the Vas(the tube transporting sperms from testis) and various semen abnormalities. This gene is expressed in various female reproductive organs like the cervix, oviduct, ovary, and uterus and it leads to menstrual irregularities and anovulation(lack of egg liberation from ovary).

Kallmann Syndrome (KS) – It is a genetic disorder that results from abnormal release of reproductive hormones from the brain. This leads to the absence of sexual maturity(puberty) or delayed appearance of beards and moustaches, even sexual issues. It also maybe associated with the absence of the sense of smell. Most of these men/women are infertile and need long term hormonal supplements.

Robertsonian Translocations – These are typical chromosomal abnormalities that may present with reproductive dysfunction, such as oligospermia (low sperm count) in males and miscarriages and infertility in females.

Infertility is a complex problem, identification of a single causative gene is usually not possible. But now there are multiple, more advanced tests in addition to the routinely done karyotyping, like fluorescence in situ hybridization(FISH) and comparative genomic hybridisation(CGH), available to identify chromosomal abnormalities.

Once the defect is identified, couples may benefit from the technology of pre-implantation genetic testing(PGT) in conjunction with in vitro fertilization (IVF). This, in simple words, involves, taking out the egg from female partner and sperm from male-forming the embryo in the laboratory and then testing all the embryos so made for the genetic abnormality suspected.

The abnormal, diseased embryos are discarded and only the “normal” embryos are then employed to attain pregnancy. This procedure gives the couple a unique opportunity to use advanced technology to select only the normal embryos and not leave anything to chance. The baby arising from this intervention almost ensures the freedom from the genetic disease in question.

Although a couple may otherwise have no fertility problems, but IVF and PGT together can still be given a serious thought to spare the affected couple from heartache in form of an abnormal baby in cases where there is a known genetic family history.

Even in some cases of recurrent abortion, this ploy may work-these couples may not have infertility, but all pregnancies end up in abortions. All blood tests turn out to be normal in these cases.

Many of these cases turn out to be of genetic origin on advanced testing. IVF with PGT can attempt to provide a live child to such a couple. Even in couples with late marriage at an older age, where the risk of chromosomally abnormal babies increases(especially if the woman is over 37-38 year old), this technology can be used to ensure the removal of all the defective embryos.

All the babies arising from these procedures are completely normal with no long term detrimental effects, either physically or mentally. This is an excellent option to eradicate a genetic disease running in families and ensure healthy subsequent off springs.

Jindal IVF clinic prides itself as being the only clinic in the region offering all these services under one roof, right from infertility treatment to in house genetic counselling, testing and feto maternal specialists. All advanced genetic testings, including PGT are being carried out in the clinic.

For any query related to infertility & infertility treatments , contact IVF Jindal at 01724911000, 9779030507 or request a call back here

How Test Tube Babies are Born at Test Tube Baby Centre?

In-Vitro Fertilization is a blessing for couples who are unable to conceive. Issues with the fallopian tubes, sperm mobility, and ovulation problems are some of the many reasons why this could be happening. With the evolution of test tube baby technique which was introduced some 30 years ago, many couples have benefited so far.

Test Tube Baby Process

The process requires extreme medical expertise of the doctors at the Test Tube Baby Hospital. The male sperm is made to fertilize the female eggs artificially in a controlled environment. This process can take around a month at the certified test tube baby clinics.
Procedure

So, let’s take a look at the procedural details that are involved in the process.

• It starts with the woman being injected with drugs that would suppress her normal menstrual cycle. This is done for 7-10 days.
• Since one egg would not be sufficient for the process, superovulation is used where multiple eggs are produced in the women using various fertility drugs when her follicle size is suitable for ovulation.
• When the eggs reach 18mm in size, they are extracted out through vagina using the process of needle aspiration.
• The male semen is collected and the sperms are extracted to have them fertilize with the eggs in the controlled environment in the test tube baby hospital.
• The doctors then select the best embryo, (which can be more than one to increase the success rate) to be transferred to the womb through a small catheter which is inserted through the vagina.

IVF is a safe method for producing healthy babies for couples who are unable to do so naturally. Visit our hospital or contact us today to know more about the procedural details involved with the process.

Top 10 Ways to Ensure High Success Rates For IVF

The IVF process is both an expensive and stressful process for a lot of people, however, tips and hints of what to do prior to entering an IVF center in Chandigarh can make a huge difference.

The thing is, when you apply the tips we are share in this article, we’re going to double the success rate for you.

Step 1 – Detox

Whenever you visit any hospital, certain tests are advised to assess the exact treatment required.
When you detox, you are bringing your body back to its natural state. You are removing toxins that have been built up in your body which can impact the test negatively.

So just relax and indulge in activities you like e.g. jogging, singing or dancing.

Step 2 – Nutrition

The detox shouldn’t take very long. But it should lead into a diet that can boost your success rate. Balanced diet helps in producing good quality eggs and sperms during treatment.

Step 3 – Acupuncture

Some specialists proclaim this by reducing stress, enhance ovarian functions along with increasing the blood supply in reproductive organs.

Step 4 – Having Sex

Many IVF treatment clinics may not recommend this, we certainly recommend. In many cases when the IVF journey begins, sex goes out the window. But sex is a feel-good factor for parents. It can help in relieving stress amongst other things.

Step 5 – Things the Women Should Do

This step is focusing more on what the ladies should do and that is taking a good quality multi-vitamin. For the best results, a vitamin that contains all the following is best: Vitamins, A, B, C complex, and E, magnesium, zinc, selenium, iron, and finally Co-enzyme Q10. Furthermore having pills or foods with high amounts of Folic acid will help in preventing neural tube defects.

Step 6 – Plan For The Wait

After your transfer, you are spending a lot of time waiting. Two weeks of waiting for the implantation to happen in fact. In this particular step it’s important to plan, but also approach this two week period in a different light.

Medically speaking, it doesn’t make a difference how you feel during those two weeks, stressed or positive. But common sense would say that stress certainly doesn’t help things at all. So do yourself a favor and plan out the next two weeks and make the best of them by joining some relaxed hobby like knitting or painting or pottery making.

Step 7 – Things The Men Should Do

For men it’s pretty simple, stay cool. Things like hot baths, steam rooms, Jacuzzis, and long distant cycling have all been linked to lowering sperm quality. So refrain from this. Furthermore, men should be drinking at least 2 liters of water a day. Dehydration is a known culprit for dampening sperm quality.

As for vitamins, ideally speak to a qualified nutritionals about an ideal multi-vitamin to take. Also make sure that if you’re on medication, you check with your doctor first before taking any multi-vitamins.

Step 8 – Exercise

The ideal body mass index for a woman should be between 20 and 25. Anything higher than that will have an effect on hormone levels. Also note that when you start the IVF cycle you want to avoid strenuous exercises such as Pilates and pushups..

Step 9 – Talking To One Another

Guys sometimes have difficulties conveying their feelings at times, but they can feel how much you feel as well. During this step you want to make sure you spend time talking about this. For men, a lot of times it takes men to process everything that’s going on and that’s alright. The idea here is to let them be and talk it out later.

This is simply how guys are by nature so don’t think of it as them being uncaring or distant. They care. Deeply.

Step 10 – Avoid Smoking & Alcohol

The last step is a given, but it’s still an important one to note as well. Any kind of smoking at all can put a damper on the quality of both sperms and eggs. Furthermore drinking in excess can lead to lower quality sperm as well. Studies have shown lower pregnancy rates in couples when the man drinks over 10 units per week.

How to Know if You are Infertile

Infertility is a condition that is devastating for couples who figure it out eventually that one of them is infertile. As for the reasons of infertility they can be numerous. For women, generally, infertility issues only increase with age.

But the only way to find out for certain is by visiting a Infertility treatment center even if you have not tried actively for fertility so far.

That being said, there are some common signs and symptoms out of simply aging that you can do at home to check.

Lack Or Painful Periods

For women in particular periods are part of living when not pregnant. The average woman’s cycle overall is 28 days. Some times it’s longer, but concern rises when a woman is unable to tell when her next period might arrive. Furthermore when they do arrive if they experience any kind of pain like cramps or even if they haven’t gone through a period in months, that is some cause for concern.

In those kinds of situations you may want to check with one of the infertility specialist Chandigarh clinics.

Pain

For both men and women, pain in lower abdomen is another sign of infertility. When it comes to women, pain tends to stem from the act of sex itself. Many women experience painful sex their entire lives and think that it’s normal, when in reality it’s not. Pain during sex for women could mean a number of things from hormone issues to perhaps issues that can contribute to infertility.

For men, the pain is not actually from sex but more from pain from the testicles. Furthermore any kind of swelling as well in that area could be something that contributes to infertility too.

Again, the best way to be absolutely certain of this is to go to an infertility clinic Chandigarh and conduct some fertility tests to see.

Erections & Ejaculations

The last sign is for the men only and that is problems getting an erection and even ejaculating too. With erections, the ability to get an erection and maintain it stems from his hormone levels. Any sign of reduction in hormone levels could be a sign he is having fertility issues.

Conclusion

Infertility is a troubling thing and there is a moderate chance of it coming up. Overall, female infertility is to blame 40% of the time while for men it ranges to 30 to 40. Combining the two, fertility issues come up around 20 to 30% of the time.

But not all hope is lost if you are diagnosed with infertility or you are worried you are infertile. With the medical field continuing to grow and make advancements there are other ways to conceive now more than every before. Take some time to check in with a Infertility specialist Chandigarh clinic and discuss your options.

Source: https://www.ivfchandigarh.com/all-blogs/how-to-know-if-you-are-infertile/

Depth Understanding Of Female Infertility

Whether you are planning to have kids now, soon, or later down the road, it’s not a bad idea to go through a female fertility test now.

Even though men are just as responsible for infertility, doesn’t mean infertility in women is any less important. In fact female infertility is the overall issue in a third of infertility cases. So it’s important that we take a look at the female fertility cycle and know some signs before doing a female fertility test.

One of the most common ones for testing is not being able to get pregnant after a year of unprotected sex. That being said, there are faster methods to finding infertility in women.

Read more : https://www.ivfchandigarh.com/all-blogs/depth-understanding-of-female-infertility/

Meet Dr. Umesh Jindal, Who has treated thousands of Childless Couples

Dr. Umesh N Jindal is a pioneer; a dynamic and progressive leader with over 30 years of experience in the field of infertility. 

She was the first to start specialized infertility services in Chandigarh including assisted reproduction techniques such as IUI, IVF and ICSI. Thousands of babies have been born with these techniques. Her centre Jindal IVF and Sant Memorial Nursing Home in Sector 20 is well equipped with a state of art and ICMR and ISAR accredited IVF laboratory and equipment. Comprehensive infertility services including endoscopy, IVF-ET, ICSI, sperm bank, embryo cryofreezing, ICSI with testicular sperm and assisted hatching are provided at this centre with excellent results.

She obtained her post-graduation in Obstetrics and Gynaecology with honours medal from the premier medical institution of north India – the Postgraduate Institute of Medical Education and Research (PGI), Chandigarh in 1980 after graduating from Government Medical College, Patiala in 1977. Dr Jindal subsequently served as a senior resident and as an Assistant Professor in the WHO (CCR program) at the same Institute. She worked as a Fellow in Maternal Fetal medicine from 1982-83 at the University of Washington Seattle USA. She received her IVF/ICSI training at the Institute of Human Reproduction, Kolkata India and Reproductive Science Associates, Kansas City, USA. She has also been a visitor to many other IVF centres in USA, India and Turkey.

Read more: https://www.ivfchandigarh.com/all-blogs/meet-dr-umesh-jindal-who-has-treated-thousands-of-childless-couples/